Intrauterine Insemination (IUI) is a specialized reproductive medicine procedure developed to increase the chances of pregnancy for couples who face difficulties in conceiving naturally. During IUI, carefully selected sperm from a semen sample is introduced directly into the uterus approximately 36 hours after triggering ovulation. This process involves washing and concentrating the sperm before submitting it into the woman’s uterus through a thin catheter.
Who is IUI an Option for?
Types of IUI
Depending on how the timing of ovulation is achieved, the following types of treatment can be distinguished:
In the natural cycle approach, medication is not used for
stimulation. The natural growth of the leading follicle, which usually contains an egg, is monitored through ultrasound examinations. Once it reaches the desired size, ovulation is triggered using medication. Approximately 36 hours later, sperm is introduced into the uterine cavity through a thin catheter inserted via the cervix to enable fertilization.
Advantage: No medication-induced follicle stimulation is required
Note: The chances of success are low, so this treatment is recommended mainly for very young patients with a favorable prognosis.
Medications are used to support the female Cycle and promote the development of one or more mature follicles (up to three) to increase the chances of successful conception. This significantly enhances the chances of success, but it should be noted that this also slightly increases the risk of multiple pregnancies. The medication is administered daily throughout the process, and the treatment usually lasts 7-9 days, depending on individual response.
Similar to the natural Cycle, regular ultrasound examinations are performed every two to three days to monitor follicle development closely. Once the desired follicle size is reached, a medication triggers ovulation. We aim to optimize the timing of insemination to maximize the chances of successful fertilization and healthy pregnancy.
For insemination, the same procedure as in the natural Cycle is followed, gently introducing the prepared sperm into the uterine cavity through a thin catheter.
Fertilization Options
In this procedure, the partner provides a semen sample on fertilization, which is then prepared in the lab for insemination.
For cases requiring donor sperm, the sample is obtained from a sperm bank. General tests are conducted to rule out infectious diseases and genetic disorders, and a karyotype analysis is performed to assess the numerical and structural integrity of the chromosomes.
Donors also undergo a rigorous selection process and comprehensive evaluations, including an assessment of their personal and family history and psychological evaluations.
If you have questions or are considering IUI as a fertility treatment option, please do not hesitate to contact us. We are here to support you at every step.
Obstetrician – Gynecologist
Fertility Specialist
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